This study does not surprise me at all. Consider this:
Proton Pump Inhibitors (PPI) deplete the body of the following nutrients: Vitamin A (Beta-Carotene), Vitamin C, Vitamin B12 (Cobalamin), Chromium, Folic Acid, Iron, Zinc, Calcium, and Copper. When you consider the above, you can understand WHY people taking these drugs for long periods of time develop serious illnesses and have a higher risk of early death.
"Popular heartburn drugs called proton pump inhibitors (PPIs) have been linked to a variety of health problems, including serious kidney damage, bone fractures and dementia. Now, a new study from Washington University School of Medicine in St. Louis shows that longtime use of the drugs also is associated with an increased risk of death."
People can avoid heartburn and symptoms of GERD by losing weight, eating smaller meals, and eating their last meal hours before bedtime. Some foods that are associated with GERD are chocolate, high fat foods, spicy foods, caffeine, and alcohol. Avoiding these foods might make a huge difference in their symptoms.
Those who have special problems that require them to take PPIs need to make sure to replenish their bodies with the nutrients they lose when they are taking these drugs.